What is Ozone Therapy? Uses, Benefits, and More.

Ozone Therapy: Gentle Oxygen Support Through the Ears
At Clinic 5C Functional Medicine, we offer a unique, non-invasive approach to ozone therapy. While ozone has may methods of delivery, our most commonly used method at Clinic 5C is delivered through the ears using medical-grade equipment from Simply O3.
This method uses oxygen as its base, transforming it into ozone and delivering it safely via soft earphones. It’s a calming, passive way to support your immune system, energy production, and overall resilience without needles or IVs.
Ozone therapy may sound unconventional, but it’s been used for decades in integrative and functional medicine. Whether you’re dealing with chronic symptoms, post-viral fatigue, or are simply looking to strengthen your body’s recovery systems, this therapy may offer a gentle yet powerful reset.
How Ozone Ear Insufflation Works
Ozone (O₃) is a highly energized form of oxygen made up of three oxygen atoms. In Clinic 5C’s protocol, we use a Simply O3 generator connected to a pure oxygen source to create ozone gas. That gas is then delivered through specialized earphones while you relax in a quiet setting.
The ear canals provide a safe and effective access point, allowing ozone to reach the surrounding tissues and blood vessels. While the ears are the delivery site, the potential effects may extend systemically, helping support your body’s internal regulation processes.
Sessions are painless, take just 3 to 5 minutes, and require no downtime.
Potential Benefits of Ozone via Ear Insufflation
Ozone therapy through the ears may support:
- Recovery from illness or immune challenges
- Reduction in chronic inflammation
- Energy production and mitochondrial function
- Mental clarity and cognitive sharpness
- Detoxification and oxidative stress balance
- Sinus, ear, or upper respiratory symptoms
Many patients find it especially helpful during recovery from colds, flus, or mold-related exposures, as well as during travel, high-stress periods, or after intense treatments.
Who Might Benefit
This form of ozone therapy is ideal for those who:
- Prefer non-invasive, needle-free therapies
- Are exploring adjunctive care for chronic illness or fatigue
- Want to improve immune resilience or reduce inflammation
- Are sensitive to more aggressive therapies
- Are interested in gentle, evidence-informed wellness tools
It’s a flexible option that can be added to most functional medicine plans without interfering with other modalities.
Integrating Ozone with Functional Medicine
At Clinic 5C, ozone therapy is always personalized. While some use it as a standalone session to bounce back from illness or boost clarity, others incorporate it into larger protocols that may include IV Nutrition, PEMF, or IR sauna therapy.
Our providers will help you determine if ozone is a good fit for your symptoms, goals, and current care plan. We may also recommend baseline lab testing or gut-healing protocols to help amplify results.
What to Expect During Your Visit
Ozone ear insufflation is one of our most relaxing therapies.
- Before: Hydration is encouraged. No lab work or prep is required.
- During: You’ll wear a pair of soft earphones while reclining in a peaceful treatment room. You may feel a slight warming or pressure sensation in the ears.
- After: Most patients feel calm, clear, or lightly energized. Some report improved sinus function or sleep after the first few sessions. You may experience a lingering “pool” smell for the rest of the day, as it dissipates.
We typically recommend a series of treatments for cumulative effect, especially during active healing phases or immune stress.
Explore Functional Medicine Therapies
Ozone therapy pairs well with IV Nutrition, sauna, red light, and PEMF. This is especially true if your goals include lowering inflammation, increasing resilience, or optimizing recovery. Ask our team how to combine modalities for maximum benefit.
Learn More or Book a Session
If you’re interested in exploring oxygen-based therapies to support your energy, immunity, and long-term vitality, ozone may be an excellent place to start.
Call Clinic 5C to schedule a session or ask how it fits within your personalized care plan. Members in our Longevity or Functional Medicine programs receive exclusive access and bundled pricing for ozone and other regenerative tools.